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Mastivet plus (Suspension for intramammatory infusion)
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Mastivet plus (Suspension for intramammatory infusion)

...DESCRIPTION
Oily suspension from white to yellowish color, with specific odor of the components.
COMPOSITION
Each1 ml contains an active ingredients:
amoxicillin trihydrate – 50.0 mg
Prednisolone – 1.0 mg.
PHARMACOLOGICAL PROPERTIES
The active ingredient of the preparation is an antibiotic - amoxicillin. Amoxicillin belongs to a group of β-lactam antibiotics. It blocks the synthesis of cell walls of the bacteria, slows the enzyme activity of transpeptidase and carboxypeptidase, causes osmotic balance disturbance, which resulting to the death of microorganisms during the stage of development.
The preparation is active against gram-positive (Actinomycos spp., Bacillus antracis, Cloctridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Streptococcus spp., Listeria monocytogenes) and gram-negative (Actinobacillus app., Bordetella bronchiseptica, Fusobacterium spp., Haemophilus app., Moraxella spp ., Pasteurella app., Proteus mirabilis, Salmonella spp.) microorganisms. Insensitive to the preparation such microorganisms as: Pseodomonas aeruginosa, Serratia, indole-positive Proteus (except Proteus mirabilis), Enterobacter spp, Citrobacter spp and Acinetobacter spp.
Prednisolone is a dehydrated analogue of hydrocortisone. It has anti-inflammatory, desensitizing and anti-allergic effect, and anti-shock and antitoxic properties. Stimulating steroid receptors, induces formation of a special class of proteins – lipocortins (annexin) that decongestants have activity as well as reduces the activity of hyaluronidase, and helps reduce the capillary permeability.
INDICATIONS
Cattle, sheep and goats suffering from subclinical and clinical mastitis forms of bacterial etiology, caused by pathogens susceptible to amoxicillin.
DOSAGE
Intramammary at the following doses:
Cattle:  ½ the content of one syringe tube depending on the severity of the disease (or 5 – 10 ml of the suspension) administered 1 time per day in each affected quarter of the udder, which previously milked and disinfected.
Sheep, goats:  ¼ or ½ the content of the syringe tube depending on the severity of the disease (or 2.5 – 5 ml of the suspension) administered 1-2 times per day in each affected quarter of the udder, which previously milked and disinfected.
After the administration, the udder quarters should be massaged for evenly distribution throughout its cisterns.
Duration of treatment is 5-7 days.
CONTRAINDICATION
Hypersensitivity to penicillin group or other drugs β-lactam group.
Do not use in viral and fungal diseases.
Do not use in conjunction with cephalosporin antibiotics, tetracyclines, macrolides.
PRECAUTIONS
Animals may only be slaughtered for human consumption after 14 days from the last treatment.
The milk might be taken for human consumption after 4 days from the last treatment.
HOW SUPPLIED
Disposable tubes of 10 ml.
STORAGE
In a dark, dry place, at 10ºС – 25ºС.
Keep out of reach of children and away from food.
Shelf life: 12 months.


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