Gentavet 10% solution
...DESCRIPTION
Transparent colorless solution.
COMPOSITION
Each 1 ml contains the active ingredient:
gentamicin sulphate – 100,0 mg.
PHARMACOLOGICAL PROPERTIES
ATCvet QJ01 - antibacterial veterinary medicines for systemic use (QJ01GB03, Gentamicin).
Gentamicin – an antibiotic that belongs to a group of aminoglycosides. It is active against the gram-negative and gram-positive microorganisms: Escherichia coli, Salmonella spp., Shigella spp., Enterobacter aerogenes, Klebsiella spp., some species of Proteus spp. and Serratia spp., Pseudomonas aeruginosa, Pasteurella multocida, Starhylococcus aureus, Serpulina hyodysenteriae, Mycoplasma spp.
The mechanism of action of the preparation is to block protein synthesis in bacterial cells.
Approximately 30% of the antibiotic is bound to plasma proteins.
The mechanism of action is to block protein synthesis in bacterial cells.
Resistance to it is rare and slow to develop.
The maximum drug concentration in blood serum is observed one hour after administration. Therapeutic concentrations stored in the body 8 to 12 hours. Gentamicin is also penetrating into the pleural and peritoneal cavity and placenta. In the active form excreted by the kidneys.
INDICATIONS
Calves less than 3months old, pigs: the treatment of animals suffering from septicemia, arthritis, also from diseases of gastrointestinal tract (gastritis, enteritis, peritonitis), respiratory organs (tonsillitis, tracheitis, pneumonia, bronchitis, bronchopneumonia) and genitourinary (nephritis, pyelitis, pyelonephritis, urethritis, urocistitis, metritis, mastitis), skin (dermatitis) caused by pathogens susceptible to gentamicin.
Poultry (chickens, turkeys, ducks, geese): treatment of poultry suffering from septicemia, colibatcilosis, pasteurellosis, salmonellosis caused by pathogens susceptible to gentamicin.
DOSAGE
Orally in doses:
calves – the first day – 5 ml of the preparation per 100 kg of body weight (divided into two times), then – 4 ml of the preparation per 100 kg of body weight once a day.
pigs – 5 ml of the preparation per 100 kg of body weight per day (divided into two times) or 5 ml of the preparation per 10 liters of drinking water. For the treatment of dysentery – 11-22 ml per 100 liters of drinking water.
poultry (chickens, turkeys, ducks, geese) – 20 ml of the preparation per 100 liters of drinking water.
The course of treatment – 5-7 days.
CONTRAINDICATIONS
Hypersensitivity to gentamicin.
Do not used for animals with impaired renal function, hearing and balance.
Do not use simultaneously with other aminoglycosides and antibiotics with nephrotoxic effect (polymyxin B, colistin, amfotercin, chloramphenicol, cephalosporin, ritromycin), also with muscle relaxants and anesthetics, sulfonamides, heparin, B vitamins, diuretics (furosemide).
Do not administer to laying hens producing eggs for human consumption.
PRECAUTIONS
Animals may only be slaughtered for meat after 7 days after the last treatment.
HOW SUPPLIED
Flacons of neutral glass of 10, 50 and 100 ml. Outer packaging – cardboard box.
Polymeric containers (bottles) in 500 ml and 1 liter.
STORAGE
Dry, dark, inaccessible to children place at temperature from 5°C to 25°C.
Shelf life – 2 years.
After the first selection from the vial, the medicine should be used within 14 days, provided storage in a dark place at a temperature of 0°C to 5°C.