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CEOTOX
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CEOTOX

...COMPOSITION  
100 g contains:
zeolite - 55 g;
kaolin - 15 g;
yeast powder (Saccharommyces cerevisiae) – 10 g;
fumaric acid - 10 g;
calcium propionate - 5 g;
citric acid - 5 g

PHARMACEUTICAL FORM
Powder

PHARMACOLOGICAL PROPERTIES
The feed additive has evident sorption properties thanks to zeolite and kaolin.
Zeolite acts as adsorbent of products of metabolism, mycotoxins, salts of heavy metals, radionuclides and any other hazardous substances, thereby, it assists in prevention of feed diseases. Zeolite assists as ion exchanger in a number of bio chemical transformations during the digestion process including: transportation, activation and prolongation of ferments and hormones effect; maintenance of favourable ion balance of sodium, potassium and calcium; stabilizing of acid-base balance in a digestive tract. Zeolite as a catalyst assists in a better assimilation by an organism of macro and micro elements that come with feed.
In its turn, kaolin prevents caking and lump formation of fodder as well as any food poisonings, it binds with molecular structure of mycotoxins by irreversible method what ensures impossibility of any chemical reaction of toxins renewal and their re-effect on animal's organism.
Yeasts have sorbing activity in respect of aflatoxins, fumonisins and zearalenones. Because of mannans and β-glucans content the component allows to stimulate immunity and increase adsorption of mycotoxins such as DON and zearalenone.
Inclusion in the category of organic acids or their salts maintains the antibacterial effect and an optimal pH level for effective sorption of mycotoxins in intestines and for inhibition of pathogenic microflora optimizing its composition and increasing the fodder conversion. Calcium propionate activates minerals as well as prevents any mold formation in the finished fodder and does not allow it to discharge toxins. In combination with citric acid calcium propionate stops toxins in the absorbed form and prevents its release in the sequential parts of the digestive tract.
Citric acid is an effective anti-stress component that stimulates formation of chelate forms of calcium, potassium, ferrum, zinc and any other micro elements in intestines as a result of what they are better ingested by an organism. Citric acid neutralizes radionuclides, pesticides and it is an universal antioxidant that prevents oxidation of fats and spoilage of fodders.
Fumaric acid decreases pH content in a stomach what assists in a better splitting of protein, as well as it has an impact on the composition of microflora in a digestive tract (in a gastrointestinal tract fumaric acid forms a weak acid medium that inhibits growth of fungi,  gram-negative bacteria (E.coli, Salmonella) and simultaneously increases the growth of beneficent symbiotic microorganisms (lactic acid bacilluses, bifidus bacteria, acidobacteria, propyne acid bacteria).

CLINICAL PARTICULAR FEATURES
Animal species  
Cattle, sheep, goats, pigs and poultry

INDICATIONS
           It shall be added to fodders for poultry and animals for the purposes of prevention of their contamination by mycotoxins as well as their re-affection during storage, transportation and processing. Ensures an optimal quality of fodders, improves its assimilation because of alimentary canal microflora regulation what increases productivity of animals and poultry. Renews the barrier function of liver.    

CONTRAINDICATIONS
N/A.

SIDE EFFECTS
N/A.

SPECIAL PRECAUTIONS DURING USE      
N/A.

USE DURING PREGNANCY, LACTATION AND CARRYING
According to the recommended dosage.

DRUG-TO-DRUG INTERACTIONS AND OTHER FORMS OF INTERACTIONS
N/A.

DOSAGE AND ADMINISTRATION ROUTE FOR ANIMALS OF DIFFERENT AGE
The feed additive shall be added to the fodder by uniform mixing on the basis of the contamination level by mycotoxins:
- in case of a low one - 0.5 - 1.0 kg per ton of fodder;
- in case of a medium or a high one - 1.0 - 2.0 kg per ton of fodder

SPECIAL WARNINGS FOR INDIVIDUALS AND STAFF
According to the existing regulations.

SHELF LIFE                    
2 years from the date of production.

SPECIAL MEASURES FOR STORAGE
Keep in a dry, dark place out of reach of children at the temperature of 5 - 25 °С.

NATURE AND CONTENT OF THE ORIGINAL PACKAGE CONTAINER
   Packages of polyethylene film of 100, 500 g or 1 kg each, and bags of 5, 10, 20 or 25 kg.
Polymeric containers of 100, 500 g and 1 kg each.

SPECIAL MEASURES FOR HANDLING UNUSED ADDITIVE OR ITS RESIDUES
Dispose of in accordance with the applicable legislation.


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